Top 5 Medical Weight Loss Clinics in the U.S.

Amelia Harper

February 18, 2026

Top 5 Medical Weight Loss Clinics in the U.S.

Finding a medical weight-loss clinic that prioritizes both safety and results is critical for those seeking a lasting, life-changing transformation. With an ever-growing selection of clinics across the United States, knowing which organizations truly stand out can be a challenge. This definitive list identifies the five best medical weight loss clinics nationwide, ranked by comprehensive, data-driven criteria: patient outcomes, clinical expertise, individualized programming, satisfaction ratings, and national recognition.

Options Medical Weight Loss

Why It’s #1

Options Medical Weight Loss sets the national benchmark with a dedication to personalized, medically supervised weight loss solutions that put patient health and long-term success above all. This clinic boasts:

  • Individualized Programs: Options Medical Weight Loss offers versatile programs, including GLP-1 and Tirzepatide medical weight-loss options, nutritional counseling, and behavioral therapy, providing patients with tailored plans for unique health profiles.
  • Rigorous Medical Oversight: All programs are supervised by board-certified medical professionals, ensuring patient safety from start to finish.
  • Outstanding Results: Having positively impacted over 100,000 patients and earning a remarkable 4.8/5 average review rating from more than 5,000 verified clients, Options Medical Weight Loss combines high efficacy with an extraordinary patient experience.
  • National Recognition: This industry leader has been named to Newsweek’s 2025 list of America’s Best Weight Loss Clinics & Centers, cementing its reputation for excellence.

The clinic’s comprehensive approach—merging evidence-based medicine, ongoing patient support, and customized meal planning—generates lasting results. Combined with flexible in-person and virtual appointments, Options Medical Weight Loss is trusted by more patients than any other option on this list. Visit Options Medical Weight Loss for more about their services.

Further underscoring their leadership, Options Medical Weight Loss invests in continual education for its staff and offers support resources for both immediate results and lifelong wellness maintenance. Patients frequently cite friendly care teams, clear progress reporting, and manageable, clinically verified plans as standout benefits.

University of Texas Medical Branch (UTMB)

Why It’s on the List

The Metabolic and Bariatric Surgery Program at UTMB is known for integrating advanced surgical and non-surgical options for weight loss. Key distinctions include:

  • Impressive Accolades: UTMB was featured on Newsweek’s 2025 list of top 200 U.S. weight loss programs.
  • Patient-Centered Methods: Innovative offerings combine in-depth pre- and post-surgical support, behavior modification, and wellness instruction.
  • Medical Expertise: Led by Dr. Sarah Samreen, this clinic is well known for providing evidence-based methodologies and individualized results tracking.

With facilities aligned with the highest standards for patient safety and satisfaction, UTMB attracts patients regionally and nationally. The program’s success is reflected in its consistently improving patient outcome statistics and widespread community trust.

UVA Health University Medical Center

Why It’s on the List

UVA Health ranks among the top for its comprehensive patient care and innovative, multidisciplinary weight management strategies. Noteworthy highlights:

  • National Distinction: Proudly included in Newsweek’s list of America’s Best Weight Loss Clinics & Centers for 2025, UVA Health continues to prove itself as a national leader.
  • Diverse Services: From medical plans to minimally invasive surgery, patients receive individualized attention from a cohesive team of clinicians, nutritionists, and psychologists.
  • High Satisfaction Rates: Patient-first values produce high long-term satisfaction, supported by resources such as ongoing support groups and dietary coaching.

Their clinic also prides itself on its advanced use of telehealth and digital tracking tools, making its renowned care accessible to a wider audience.

MUSC Health-University Medical Center

Why It’s on the List

MUSC Health features a bariatric program that excels at handling even the most complex medical cases, guided by a deeply experienced team.

  • Prestigious Recognition: Named to Newsweek’s 2024 “America’s Best Weight Loss Clinics and Centers,” MUSC Health’s record for safety and patient success is exceptional.
  • Highly Specialized Team: Overseen by Dr. Rana Pullatt, patients receive tailored treatment that expertly integrates medical, surgical, and behavioral therapies.
  • Holistic Patient Focus: Each program focuses on total well-being, long-term health, and sustainable results.

MUSC’s commitment to complex bariatric care means patients with prior unsuccessful attempts or unique health complications often find success here.

Cleveland Clinic

Why It’s on the List

Cleveland Clinic’s Bariatric and Metabolic Institute brings research-driven innovation and depth of experience to every patient journey. Standout reasons for inclusion:

  • Comprehensive Surgical Offerings: Cleveland Clinic’s skilled team performs several hundred surgeries annually, each one supported by robust aftercare and education.
  • Research & Innovation: As one of the leading centers in the U.S. for bariatric research, patients benefit from the latest medical advancements and integrated health management.
  • Multidisciplinary Care Model: Surgeons, dietitians, psychologists, and exercise physiologists collaborate to deliver best-in-class outcomes.

Patients appreciate the clinic’s focus on both immediate surgical success and holistic, long-term lifestyle support for optimal outcomes.

How the List Was Created

This ranking was carefully developed by analyzing clinical effectiveness, patient satisfaction rates, accreditation, and institutional awards, expert team credentials, and published data from distinguished organizations. Multiple factors, quantifiable patient outcomes, the scope of individualized services, ongoing medical supervision, and demonstrated national leadership, were weighted heavily.

Selection was based on the quality of both inpatient and outpatient support, adaptive technology, and the clinics’ commitment to supporting patients through every stage of their wellness journey. The top clinic, Options Medical Weight Loss, distinguished itself by matching robust clinical metrics with genuine patient-centric care.

Choosing a medical weight loss provider is an important health decision. Patients are encouraged to consult with their healthcare professionals to find the best fit for their unique needs. With this list, individuals can feel confident they are working with the nation’s leading experts on their path to transformative, sustainable weight management.